Other people develop TTP after having another condition. Doctors call this “acquired thrombotic thrombocytopenic purpura,” which is unrelated to issues with the ADAMTS13 gene. Instead, the body produces antibodies that cause the enzyme to malfunction. Your doctor may start you on a corticosteroid medication, which can help increase your platelet count by decreasing the activity of your immune system. It usually takes about two to six weeks for your platelet count to return to a safe level. When it does, your doctor will discontinue the drug. Lotti T, Benci M, Sarti MG, Teofoli P, Senesi C, Bonan P, etal. (1993). "Psychogenic purpura with abnormally increased tPA dependent cutaneous fibrinolytic activity". International Journal of Dermatology. 32 (7): 521–23. doi: 10.1111/j.1365-4362.1993.tb02840.x. PMID 8340191. S2CID 38433734. Unlike other rashes, purpura will not change color or blanch when pressed. The rash can resemble tiny clusters of bruises. While the skin will not be itchy or painful in many cases, some tenderness or irritation may sometimes occur.

Thrombocytopenic purpura and petechiae: These occur due to conditions that cause the irregular destruction of blood platelets — cell fragments that help the blood clot. Autoimmune conditions or certain medications or infections can have this effect.The outlook for purpura depends on the underlying condition causing it. When your doctor confirms a diagnosis, they’ll discuss treatment options and the long-term outlook for your condition. Doctors do not know the exact cause of Henoch Schönlein purpura. However, it could occur due to inflammation of the blood vessels, also known as vasculitis. It is the most common type of vasculitis in children in North America. PURPURA English Definition and Meaning | Lexico.com". Archived from the original on October 17, 2019.

Microvascular injury, as seen in senile (old age) purpura, when blood vessels are more easily damaged Steroid treatment can reduce kidney damage and abdominal pain. Doctors may prescribe drugs to suppress the immune system if kidney damage is severe.People with thrombotic thrombocytopenic purpura (TTP) do not have enough of the enzyme ADAMTS13, which controls blood clotting. This means a person produces too many blood clots. Purpura, also called blood spots or skin hemorrhages, refers to purple-colored spots that are most recognizable on the skin. The spots may also appear on organs or mucous membranes, including the membranes on the inside of the mouth. Heparin-induced thrombocytopenia: Occurs when a negative reaction to the drug heparin makes your body clot too much.

Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. If invasive meningococcal disease is suspected, administer parenteral antibiotics immediately, but do not delay hospital admission Extravasated blood usually breaks down and changes colour over a few weeks from purple, orange, brown and even blue and green. Classification of purpura Asif M, et al. (2019). A multidisciplinary approach to the management of severe purpura fulminans in a burn center: A case study.A purpura cluster is not generally irritating or itchy. The spots are also non-blanching, meaning that they do not fade or change color under pressure. When purpura spots are very small (<1 cm in diameter), they are called petechiae or petechial haemorrhages. Larger, deeper purpura are referred to as ecchymoses or bruising. In some cases, doctors recommend NSAIDs to reduce inflammation and pain. However, people with gastrointestinal or kidney issues should avoid these medications.